ANALISIS PENGGUNAAN PRE EXPOSURE PROPHYLAXIS (PrEP) TERHADAP KEJADIAN INFEKSI MENULAR SEKSUAL PADA LELAKI SEKS LELAKI: A LITERATUR REVIEW
DOI:
https://doi.org/10.51712/mitraraflesia.v16i2.395Abstract
ABSTRAK
Latar Belakang : Salah satu program pencegahan terbaru terhadap HIV yang dilakukan oleh pemerintah sesuai rekomendasi WHO adalah terapi pemberian ARV Profilaksis sebagai tambahan dari upaya program pencegahan komprehensif untuk mengakhiri epidemi HIV pada tahun 2030. Seiring meningkatnya penggunaan PrEP di kalangan populasi LSL, kejadian IMS mulai menjadi perhatian.
Metode : Mengacu pada pendekatan studi literatur dalam rentang waktu 6 tahun terakhir (2018-2023) penelitian ini bertujuan untuk mempelajari hubungan penggunaan PrEP dengan kejadian Infeksi Menular Seksual. Penelitian ini dirancang untuk melakukan review literatur dengan menggunakan metode PRISMA (Preferred Reporting Items for Systematic Reviews and Meta Analysis). Penelitian ini dilakukan melalui pencarian artikel bersumber dari Google scholar dan Pubmed. Artikel penelitian asli yang dipublikasikan selama enam tahun terakhir mulai tahun 2018-2023 adalah kriteria yang dimasukkan dalam penulisan ini.
Hasil : Dari hasil telaah literatur, penggunaan PrEP mempengaruhi prilaku seksual pasangan LSL seperti hubungan seksual tanpa menggunakan kondom. Perubahan prilaku ini dapat meningkatkan kejadian IMS di kalangan populasi LSL. Akan tetapi tidak ada hubungan antara penggunaan PrEP dengan meningkatnya kejadian IMS di kalangan populasi LSL.
Kesimpulan : Dari analisis yang dilakukan terhadap hubungan  penggunaan PrEP dengan kejadian IMS pada 7 artikel yang ditelaah, penggunaan PrEP tidak berhubungan secara langsung dengan meningkatnya kejadian IMS. Meskipun PrEP telah berkontribusi terhadap perubahan perilaku seksual di kalangan LSL, dampaknya terhadap kejadian IMS masih belum pasti. Meningkatnya jumlah bakteri IMS di kalangan LSL terjadi sebelum meluasnya penggunaan PrEP dan PrEP tidak menyebabkan epidemi IMS saat ini.Â
Kata kunci: HIV, Pre Exposure Prophylaxis, Infeksi Menular Seksual
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ABSTRACT
Background : One of the latest HIV prevention programs undertaken by the government as recommended by WHO is prophylactic antiretroviral therapy in addition to comprehensive prevention program efforts to end the HIV epidemic by 2030. As PrEP use increases among the MSM population, the incidence of STIs begins to become a concern.
Method : Referring to the literature study approach in the last 6 years (2018-2023) this study aims to study the relationship between PrEP use and the incidence of Sexually Transmitted Infections. This study was designed to conduct a literature review using the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta Analysis) method. This research was conducted through searching articles sourced from Google scholar and Pubmed. Original research articles published over the past six years from 2018-2023 are the criteria included in this writing.
Results : From the results of a literature review, PrEP use affects the sexual behavior of MSM couples such as sexual intercourse without using a condom. These behavioral changes can increase the incidence of STIs among the MSM population. However, there was no association between PrEP use and an increased incidence of STIs among the MSM population.
Conclusion : From an analysis of the relationship between PrEP use and the incidence of STIs in the 7 articles reviewed, PrEP use was not directly associated with an increased incidence of STIs. Although PrEP has contributed to changes in sexual behavior among MSM, its impact on the incidence of STIs remains uncertain. The increasing number of bacterial STIs among MSM occurred before the widespread use of PrEP and PrEP did not cause the current STI epidemic.Â
Keywords: HIV, Pre Exposure Prophylaxis, Sexually Transmitted InfectionsÂ
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